Wells’ score adjusted D-dimer in diagnosis of Pulmonary Embolism
Combination of clinical prediction tool and D-dimer should be used in diagnostic algorithm for most cases of suspected pulmonary embolism. Current practice use cut-off of 500 ng/ml for negative in low probability cases. Pulmonary Embolism Graduated D-Dimer (PEGeD) Study looked at the use of D-dimer adjusted to clinical probability in order to decrease the burden of diagnostic imaging in selected patients.